PBTC Progress to Date

The Consortium enrolled its first patient in February 2000. 

As of July 1, 2014:

Patients accrued to date

1480

Number of therapeutic protocols open

7
SAHA + Isotretinoin (feasibility);
ABT-888 + RT (phase I/II);
Imetelstat (Molecular Biology and Phase II);
AZD6244 (phase II);
p28 (phase I);
HSV1716;
PegIntron;

Number of therapeutic protocols closed

30
IT mafosfamide in infants (phase I/II) ;

SU5416 (phase I);
SCH 66336 (phase I);
IT Busulfan (phase I);
O6-BG & Temodar (phase I);
STI571 (phase II);

ZD1839 + RT(phase II);

Gliadel & O6-BG (phase I);
Oxaliplatin (phase II);

Intratumoral IL-13 (phase I/II);

Celengitide
(phase I)
;
TP-38 (phase I/II);
Zarnestra + RT (phase I);

O6-BG & Temodar (phase II);

GW572016 (phase I/II);
VNP40101M (phase I);
CC-5013 (phase I)
;
Intratumoral Topotecan (phase I);
Capecitabine + RT (phase I);
Avastin + Irinotecan (phase II);
Enzastaurin (phase I);
MK-0752 (phase I);
GDC-0449 (phase I);
ABT-888 + Temozolomide (phase I);
Capecitabine + RT (phase II);
AZD2171 (phase I);
GDC-0449 - Adult (phase II);
PTC299 (phase I);
AZD6244 (phase I);
GDC-0449 (phase II);

Number of therapeutic protocols in development

3

Number of non-therapeutic protocols open

1

Number of non-therapeutic protocols closed

7

Number of non-therapeutic protocols in development

1

Number of concepts reviewed to date

134

 

 

 

 

 

 

 

 

 

 

 

 



 


 

 

 

 

 

 

 

 

PBTC Web Site

Introduction to PBTC

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